Vpx is Critical for SIVmne infection of pigtail macaques
نویسندگان
چکیده
منابع مشابه
Dynamics of simian immunodeficiency virus SIVmac239 infection in pigtail macaques.
Pigtail macaques (PTM) are an excellent model for HIV research; however, the dynamics of simian immunodeficiency virus (SIV) SIVmac239 infection in PTM have not been fully evaluated. We studied nine PTM prior to infection, during acute and chronic SIVmac239 infections, until progression to AIDS. We found PTM manifest clinical AIDS more rapidly than rhesus macaques (RM), as AIDS-defining events ...
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Release of granzymes and perforin from the cytolytic granules of SIV-specific CD8 T cells is a critically important effector mechanism facilitating the elimination of SIV-infected cells. We sequenced granzyme A, B, and K and perforin in pigtail macaques and defined polymorphisms between humans, rhesus macaques, and pigtail macaques. The pigtail macaque sequences were similar to the correspondin...
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OBJECTIVE The aims of this study were to investigate genealogical and demographic influences on maternal abuse and neglect of offspring in pigtail macaques and identify some maternal and infant characteristics that may be risk factors for abuse or neglect. METHOD Infant abuse and neglect were investigated in five large families of group-living pigtail macaques over a period of 33-years (5-7 g...
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This study investigated whether pigtail macaque mothers encourage their infants’ independent locomotion by increasing distance from them and displaying a retrieval signal, the pucker face. Fifteen mother–infant pairs living in a large captive social group were focally observed during the first 12 weeks of infant life. Mothers puckered to their infants only when out of contact with them, and the...
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As part of a behavioral intervention program that identifies and treats individual nonhuman primates exhibiting abnormal behavior, five individually housed pigtail macaques (Macaca nemestrina) were provided with multiple cage toys in an effort to reduce high levels of abnormal behavior. Ten 30-min observations of each subject were conducted during the baseline condition and again after novel to...
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ژورنال
عنوان ژورنال: Retrovirology
سال: 2012
ISSN: 1742-4690
DOI: 10.1186/1742-4690-9-32